Tissue Depletion

Decreased quantity of a dhatu caused by high dhatu agni leading to reduced production of that tissue.

Dhatu Kshaya: Tissue Decrease

When an aggravated dosha enters a dhatu and causes high agni (tikshna agni), there is decreased production of the dhatu, called dhatu kshaya. This represents the quantitative reduction of a tissue. As with dhatu vruddhi, qualitative changes (dhatu dushti) can accompany the quantitative decrease, creating compound tissue disorders.

Source: Textbook of Ayurveda: Fundamental Principles, Chapter Five: Dhatus Part I (Rasa, Rakta, Mamsa)

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