Guggulu for Goiter: Does It Work?
Does Guggulu (Indian Bdellium, Commiphora mukul / wightii) help with goiter? Yes, but almost never as plain resin. The classical Ayurvedic answer to a thyroid swelling is Kanchanara Guggulu, the compound that pairs purified Guggulu with Kanchanara (Orchid Tree) bark. The Sharangadhara Samhita (Madhyama Khanda) records this preparation under the Guggulu Kalpas indicated for Galaganda (goiter) and Granthi (nodular masses) of the neck. It is the textbook intervention for the soft or rope-like swelling at the front of the throat that classical authors recognised as Galaganda.
Ayurveda frames goiter as a Kapha-Medas swelling at the throat, accumulated Kapha and fat tissue (Meda Dhatu) obstructing the local channels, often with a Vata component that drives nodularity and a Pitta component when autoimmune heat is added. Guggulu's classical actions almost exactly invert this pathology. The Bhavaprakash Nighantu names Guggulu Lekhana (scraping, mass-reducing), Medohara (reduces fat tissue), Shothaghna (anti-inflammatory), and Vatakaphaghna (pacifies Vata and Kapha). Its rasa is bitter and pungent (Tikta-Katu), guna light and dry (Laghu-Ruksha), virya hot (Ushna), vipaka pungent (Katu). A heavy, cold, sticky throat swelling meets a resin that is the opposite on every axis. Guggulu's defining yogavahi property, the ability to carry other herbs deeper into the tissues, is what makes Kanchanara Guggulu effective: the Bauhinia bark targets glandular accumulation, and the Guggulu delivers it.
Critical framing before any herb: goiter is a clinical diagnosis that requires a thyroid workup first, TSH, free T4, and a neck ultrasound at minimum. A visible throat swelling can be iodine-deficiency goiter, multinodular goiter, an autoimmune goiter (Hashimoto's or Graves'), or rarely a thyroid malignancy. Each pattern needs different management. If you are hypothyroid, levothyroxine is usually non-negotiable; if you are hyperthyroid or autoimmune, endocrinology supervision is mandatory. Kanchanara Guggulu is an adjunct for confirmed benign Kapha-Medas pattern goiter, used alongside, not in place of, conventional thyroid care. Do not stop prescribed thyroid medication on your own. The rest of this page covers what Guggulu can realistically do once your thyroid status is known.
How Guggulu Helps with Goiter
Guggulu's energetics are a near-inversion of the tissue picture in Galaganda. Classical authors describe the throat swelling as accumulated, sticky, cold, fluid- and fat-laden tissue lodged in the front-of-neck channels, the heaviness of Kapha layered on stagnant Meda Dhatu, with a Vata component driving nodularity and a Pitta component when autoimmune heat is involved. Guggulu is bitter and pungent in taste (Tikta-Katu Rasa), light and dry in quality (Laghu-Ruksha Guna), hot in potency (Ushna Virya), and pungent in vipaka. Bitter and pungent rasa mobilise Kapha; light and dry guna cut through the doughy stickiness; hot potency rekindles digestive fire (Agni) that normally clears Ama from the channels; pungent vipaka holds that scraping effect long after digestion. The Bhavaprakash Nighantu lists Guggulu as Lekhana (scraping), Medohara (fat-tissue reducing), Shothaghna (anti-inflammatory), and Vatakaphaghna, the exact action set required for a Kapha-Medas swelling of the neck.
The Lekhana-Granthibhedana axis
Guggulu's most distinctive action is Lekhana, the scraping action. Where most anti-inflammatory herbs merely quiet the inflammatory response, Guggulu is described as physically dissolving accumulated tissue and channel deposits. In the throat context, this means it acts on stagnant Meda and Kapha in the glandular tissue, the matrix that forms a Galaganda swelling. Classical practice calls this Granthibhedana, the breaking action on a Granthi mass. The Sushruta Samhita (Nidana Sthana, Chapter 11 on Granthi, Apaci, Galaganda and related swellings) frames these neck masses as channel-blockage pathologies that need a scraping rather than purely cooling response. This is also why classical authors rarely use plain resin for the neck: they compound it with Kanchanara (Bauhinia variegata) bark, the lead herb for Granthi and Galaganda, in Kanchanara Guggulu. The Bauhinia provides the targeting, the resin provides the delivery.
Modern phytochemistry
Modern research has identified guggulsterones (E and Z isomers) as Guggulu's principal active compounds. They suppress NF-kB activation and down-regulate TNF-alpha and IL-1beta in tissue, the same inflammatory cytokines elevated in autoimmune thyroiditis. They also act on the farnesoid X receptor, which links Guggulu to lipid and bile-acid metabolism, relevant because subclinical hypothyroid pictures commonly involve raised cholesterol and sluggish hepatic clearance. There is a critical caveat: Guggulu has documented activity on thyroid hormone metabolism in animal models, which means dose adjustment of levothyroxine may be required and TSH should be monitored more often during a Kanchanara Guggulu course. The combination of classical Lekhana action on the throat tissue, anti-inflammatory action on the cytokine load, and direct interaction with thyroid hormone pathways is why Kanchanara Guggulu remains the single most quoted Ayurvedic compound for Galaganda in classical practice today, and why it is also the one that needs the closest medical co-management.
How to Use Guggulu for Goiter
For goiter, Guggulu is almost never used as plain resin. The classical strategy is to take it as Kanchanara Guggulu, the compound that pairs purified Guggulu with Bauhinia variegata bark, Triphala, ginger, and Trikatu. Kanchanara provides the Galaganda and Granthi-specific targeting; Guggulu provides the yogavahi delivery into the thyroid tissue. Do not buy "Guggulu capsules" generically for a thyroid swelling, buy the named compound.
Standard Protocol
| Formula | Best For | Standard Dose | Anupana (Vehicle) | Duration |
|---|---|---|---|---|
| Kanchanara Guggulu | The cornerstone for Galaganda, multinodular goiter, persistent neck nodularity | 500 mg to 1 g (1-2 tablets), twice daily after meals | Warm water, or warm ginger decoction for Kapha-dominant pattern | 3-6 months minimum, reassess clinically and biochemically |
| Triphala Guggulu | Adjunct phase: Ama-clearing, when goiter has metabolic features (raised lipids, weight gain) | 500 mg twice daily before meals | Warm water | 4-8 weeks, then transition to Kanchanara Guggulu |
Anupana (Vehicle) Choice
Warm water is the standard anupana for Kanchanara Guggulu. It supports the resin's Ushna Virya and Lekhana action without adding the cold, sticky, or Kapha-aggravating qualities that milk or sweetened vehicles would introduce. For a Kapha-dominant pattern (dull, doughy, slow-growing swelling, weight gain, cold extremities), a small cup of warm ginger decoction after each dose can intensify the scraping action. Avoid taking Kanchanara Guggulu with milk for goiter, the picture is already Kapha-heavy.
Sequencing: Clear Ama First
This is the single most common protocol mistake. If your tongue has a thick white coating in the morning, your appetite is dull, and you have heavy fatigue with weight gain, do not start Kanchanara Guggulu on day one. Spend the first 2-4 weeks on an Ama-clearing phase: fresh ginger tea three times daily, light khichari diet, and Triphala at night. Once the tongue clears and digestion sharpens, switch to Kanchanara Guggulu. Driving heavy resin into a Kapha-Ama terrain just pushes the obstruction deeper.
Duration and Realistic Expectations
- First 4-6 weeks: Subtle softening of throat fullness and reduced sense of pressure. Tongue coating thins, digestion sharpens.
- 2-3 months: Measurable reduction in TSH abnormality (when Kapha pattern), modest reduction in palpable swelling. Reassess with repeat ultrasound and thyroid function around month three.
- 3-6 months: The Rasayana horizon; structural reduction in nodule size in benign Kapha-Medas patterns. Autoimmune patterns rarely respond as cleanly.
Source Quality
Buy purified (Shodhita) Kanchanara Guggulu tablets from a GMP-certified manufacturer (Kottakkal, Vaidyaratnam, Baidyanath, Sandu). Raw or unpurified resin can cause skin rash and GI irritation. Look for AYUSH certification, the words Shodhita or "purified" on the label, and specified species (Commiphora mukul or wightii). Pregnancy is an absolute contraindication for any Guggulu compound.
Frequently Asked Questions
Will Kanchanara Guggulu work for hypothyroid, hyperthyroid, or euthyroid goiter?
Different patterns, different fits. Hypothyroid goiter (high TSH, low T4, slow metabolism, weight gain, cold sensitivity) is the classical Kapha-Medas picture, this is where Kanchanara Guggulu fits best, almost always alongside levothyroxine, never as a replacement. Hyperthyroid goiter (low TSH, high T4, palpitations, weight loss, heat intolerance, Graves') is a Pitta-Vata picture; Kanchanara Guggulu can have a role once thyroid storm is ruled out, but the hot potency of Guggulu means it must be paired with cooling co-herbs like Guduchi and supervised by an endocrinologist. Euthyroid goiter (normal TSH and T4 with structural swelling, often iodine-related or multinodular) is the best simple fit for Kanchanara Guggulu, provided imaging has excluded malignancy.
Can I take Kanchanara Guggulu with levothyroxine?
Usually yes, but with monitoring. Guggulsterones interact with thyroid hormone metabolism in animal studies, which means your levothyroxine dose may need adjusting during the herb course. Practical rules: take levothyroxine first thing in the morning on an empty stomach; take Kanchanara Guggulu after meals, at least four hours apart, to avoid absorption interference; recheck TSH and free T4 at 6-8 weeks after starting the herb, and again at three months. Do not stop levothyroxine on your own to "try the herb", untreated hypothyroidism is dangerous, especially in pregnancy and cardiovascular disease. Co-management with your endocrinologist is non-negotiable.
What about iodine? Should I take iodine along with the herb?
Only after a thyroid workup tells you it is iodine-deficiency goiter. In iodine-replete regions (most of urban India, most of the US, most of Europe with iodised salt), goiter is usually not caused by iodine deficiency, and adding extra iodine to an autoimmune goiter (Hashimoto's or Graves') can worsen the condition. Get a TSH, free T4, anti-TPO antibodies, and a thyroid ultrasound first. If your workup shows iodine deficiency, iodised salt or dietary iodine (seafood, dairy) covers most cases; supraphysiological iodine supplementation should be guided by your physician. Kanchanara Guggulu addresses the Kapha-Medas tissue picture; it does not provide iodine.
Guggulu versus Kanchanara, Shilajit, or Pippali for goiter, which is best?
Different jobs in the same protocol. Kanchanara is the targeting herb for Galaganda; on its own as a decoction it works on early or mild swellings. Guggulu is the carrier and scraper; combined with Kanchanara as Kanchanara Guggulu, it becomes the gold-standard tablet for established goiter. Shilajit is the deep-tissue Rasayana, useful for chronic hypothyroid pictures with fatigue and low ojas, often layered on top of Kanchanara Guggulu after the first month. Pippali kindles Agni and clears Ama upstream, used in short courses (4-6 weeks) at the start of the protocol. A working protocol commonly uses Kanchanara Guggulu at the centre with Shilajit added for chronic hypothyroid Rasayana support.
Recommended: Start Guggulu for Goiter
If you want to start using Guggulu for goiter today, the single best form is Kanchanara Guggulu tablets, 500 mg to 1 g (1-2 tablets) twice daily after meals with warm water, for 3 to 6 months. This is the Ayurvedic gold standard for Galaganda, recorded in the Sharangadhara Samhita Madhyama Khanda among the Guggulu Kalpas. Kanchanara Guggulu pairs Bauhinia variegata bark (which targets glandular accumulation) with purified Guggulu (which delivers the action into tissue).
Kitchen version: in the absence of the compound, sip warm water with 1/2 teaspoon ginger powder and 1/4 teaspoon Trikatu before meals, plus 1 teaspoon dry Kanchanara bark decoction once daily. This kindles Agni and starts mobilising Kapha while you source the tablets.
Thyroid-state fork:
- Hypothyroid (high TSH, weight gain, cold sensitivity): Kanchanara Guggulu + Shilajit 250-500 mg twice daily in warm water. Continue levothyroxine, recheck TSH at 6-8 weeks.
- Hyperthyroid (low TSH, palpitations, weight loss): Kanchanara Guggulu only under endocrinology supervision; pair with cooling Guduchi to balance Ushna Virya. Never replace antithyroid medication.
- Euthyroid multinodular (normal labs, structural swelling): Kanchanara Guggulu alone, with annual ultrasound follow-up.
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Critical safety: any neck swelling needs TSH, free T4, and a thyroid ultrasound before starting any herb. Autoimmune goiter (Hashimoto's, Graves') requires endocrinology supervision. Hypothyroid goiter usually needs levothyroxine, do not stop prescribed thyroid medication without medical supervision. Tell your doctor about Kanchanara Guggulu; guggulsterones can shift thyroid hormone dosing. Pregnancy is an absolute contraindication. Buy purified (Shodhita) Guggulu only.
Safety & Precautions
Guggulu is a powerful herb, more so than many "gentle daily tonics" in Ayurveda. Used correctly (purified, in classical formulations, at standard doses) it has a long safety record going back thousands of years. Used incorrectly, raw resin, high doses, wrong population, it can cause real problems. Here is what you need to know.
Shodhana (Purification) Is Non-Negotiable
Never consume raw Guggulu. The fresh oleo-gum resin contains irritant fractions that classical authors identified centuries ago. Bhavaprakasha describes the purification process in detail, boiling the resin in Triphala decoction, milk, or Gomutra until it forms a clean mass called Shuddha Guggulu.
Unpurified Guggulu is associated with:
- Gastrointestinal irritation, burning, nausea, diarrhoea
- Skin rashes and allergic reactions
- Hepatotoxicity, elevated liver enzymes have been reported
Every classical formulation on the market today should start from Shuddha Guggulu. Buy only from reputable manufacturers.
Drug Interactions, Important
Guggulsterones affect liver enzymes (particularly CYP3A4) and thyroid function. Known interactions:
- Thyroid medication, Guggulu modulates thyroid hormone levels. If you are on levothyroxine or have diagnosed thyrotoxicosis, do not use Guggulu without endocrinologist supervision.
- Blood-pressure medication, Guggulu has been shown to reduce the effectiveness of propranolol and diltiazem. Dose adjustment may be needed.
- Oral contraceptives, CYP3A4 induction may reduce the levels of birth-control pills. Use backup contraception or choose a different herb.
- Anticoagulants (warfarin, clopidogrel, aspirin), Guggulu has mild blood-thinning activity. Combination raises bleeding risk.
- Hypoglycaemic medication, Guggulu may enhance glucose lowering. Monitor blood sugar closely if diabetic.
- Statins, No dangerous interaction documented, but stacking two lipid-lowering agents should be supervised.
Contraindications
- Pregnancy, Classical texts consider Guggulu a uterine stimulant and potential abortifacient. Avoid completely during pregnancy.
- Breastfeeding, Insufficient safety data. Avoid.
- Thyrotoxicosis / Graves disease, Guggulu stimulates thyroid; contraindicated.
- Acute kidney infections, Bhavaprakasha-era caution; still relevant.
- Excessive uterine bleeding, heavy menstrual periods, may worsen bleeding.
- Active peptic ulcers or GERD, the herbs hot, pungent nature aggravates Pitta.
- Known liver disease, use only under practitioner supervision.
Common Side Effects
Even with properly purified Guggulu, some users report:
- Mild skin rash or itching (usually within 1–2 weeks, stop and see a practitioner)
- Loose stools or GI upset (reduce dose or take with milk)
- Headache or restlessness (Pitta aggravation, pair with cooling herbs or reduce dose)
- Nausea if taken on empty stomach, always take after food
Stop and Seek Medical Attention If...
You develop yellowing of skin or eyes, dark urine, severe abdominal pain, unusual bleeding, or a widespread rash. These are uncommon but require immediate evaluation.
Bottom line: Guggulu is safe and effective when purified, taken in classical formulas, and matched to your constitution. It is not a casual daily tonic like Amla, respect its potency, use it for the condition at hand, and rotate off once the condition resolves.
Other Herbs for Goiter
See all herbs for goiter on the Goiter page.
▶ Classical Text References (5 sources)
20 Treatment for over nourishing त मेदो नल ले मनाशनं सव म यते कुला थजूण यामाकयवमु गमधूदकम ् म त ुद डाहता र ट च ताशोधनजागरम ् मधुना फलां ल या गुडूचीमभयां घनम ् रसा जन य महतः प चमल ू य ग ु गल ु ोः शलाजतु] योग च साि नम थरसो हतः वड गं नागरं ारः काललोहरजो मधु यवामलक चूण च योगो अ त थौ यदोशिजत ् Treatments which reduce Medas- fat, Anila- Vata and Kapha are desirable; Use of Kulattha – horse gram – Dolichos Biflorus, Jurna, Shyamaka, Yava – Barley – Hordeum Vulgare, Mudga – green gram – Averr
— Astanga Hridaya, Chapter 14: Dvividha Upakramaneeya
Snehavyapat Cikitsa – treatment of bad effects :ु त ृ णो लेखन वेद ापाना नभे षजम ् त ा र टखलो ालयव यामाकको वम ् प पल यथा वं फला ौ प यागोमू गु गुलु तरोगं च नेह याप द साधनम ् Kshut, Trushna – Producing hunger, thirst, Ulleka, sveda – vomiting and perspiration, administering foods, drinks and medicines which are dry (cause dryness), use of Takrarista (fermented medicine from buttermilk), Khala – menu prepared from curds, Uddala, Yava (barley), Shyamaka, Kodrava, Pippali (long pepper), Triphala
— Astanga Hridaya, Chapter 16: Snehavidhi oleation therapy
फला प पल प यागु गु वा द वपा चतान ् नेहान ् यथा वमे तेषां योजयेद वका रणः In these conditions, fats boiled with Triphala, Pippali, Pathya, Guggulu, etc.
— Astanga Hridaya, Chapter 16: Snehavidhi oleation therapy
Herbal smoking blends – Dhuma dravyani – For Mridu- mild kind of smoke, म ृदौ त या यगु गु गुलु मु त थौणेयशैलेयनलदोशीरवालकम ् वय गकौ तीमधुक ब वम जैलवालुकम ् ीवे टकं सजरसो यामकं मदनं लवम ् श लक कुं कुमं माषा यवाः कु द ु काि तलाः नेहः फलानां साराणां मेदो म जा वसा घ ृतम ् useful drugs are-Aguru, Guggulu, Musta, sthauneya, Shaileya, Nalada, Usheera, Valaka, Varanga, Kounti, Madhuka, Bilvamajja, elavaluka, Shrivestaka, Sarjarasa, Dhyamaka, Madana, Plava, Shallaki, Kumkuma, Masha, Yava, Kunduruk
— Astanga Hridaya, Chapter 21: Dhumpana Medicated Smoking
The wound should be fumigated with the smoke of Guggulu, Aguru, Siddhartha, Hingu (Asa foetida), Sarjarasa, Patu (Salt), Sadgrantha(Acorus calamus) or leaves of Nimba (neem), mixed with ghee; Then a wick prepared from paste of Tila, ghee, honey and appropriate drugs should be placed inside the wound and also covered over.
— Astanga Hridaya, Chapter 29: Shastrakarma Vidhi
Source: Astanga Hridaya, Ch. 14, Ch. 16, Ch. 16, Ch. 21, Ch. 29
Either Rasanjana (Aqueous extract of Berberis aristata), Brihat Pancamula (Agnimantha, Shyonaka, Gambhari, Patala, Bilva), Guggulu – along with the fresh juice of Agnimnatha is suitable;
— Astanga Hridaya Sutrasthan, Dvividha Upakramaneeya
Snehavyapat Cikitsa – treatment of bad effects :ु त ृ णो लेखन वेद ापाना नभे षजम ् त ा र टखलो ालयव यामाकको वम ् प पल यथा वं फला ौ प यागोमू गु गुलु तरोगं च नेह याप द साधनम ् Kshut, Trushna – Producing hunger, thirst, Ulleka, sveda – vomiting and perspiration, administering foods, drinks and medicines which are dry (cause dryness), use of Takrarista (fermented medicine from buttermilk), Khala – menu prepared from curds, Uddala, Yava (barley), Shyamaka, Kodrava, Pippali (long pepper), Triphala
— Astanga Hridaya Sutrasthan, Snehavidhi oleation therapy
फला प पल प यागु गु वा द वपा चतान ् नेहान ् यथा वमे तेषां योजयेद वका रणः In these conditions, fats boiled with Triphala, Pippali, Pathya, Guggulu, etc.
— Astanga Hridaya Sutrasthan, Snehavidhi oleation therapy
Herbal smoking blends – Dhuma dravyani – For Mridu- mild kind of smoke, म ृदौ त या यगु गु गुलु मु त थौणेयशैलेयनलदोशीरवालकम ् वय गकौ तीमधुक ब वम जैलवालुकम ् ीवे टकं सजरसो यामकं मदनं लवम ् श लक कुं कुमं माषा यवाः कु द ु काि तलाः नेहः फलानां साराणां मेदो म जा वसा घ ृतम ् useful drugs are-Aguru, Guggulu, Musta, sthauneya, Shaileya, Nalada, Usheera, Valaka, Varanga, Kounti, Madhuka, Bilvamajja, elavaluka, Shrivestaka, Sarjarasa, Dhyamaka, Madana, Plava, Shallaki, Kumkuma, Masha, Yava, Kunduruk
— Astanga Hridaya Sutrasthan, Dhumpana Medicated Smoking
The wound should be fumigated with the smoke of Guggulu, Aguru, Siddhartha, Hingu (Asa foetida), Sarjarasa, Patu (Salt), Sadgrantha(Acorus calamus) or leaves of Nimba (neem), mixed with ghee;
— Astanga Hridaya Sutrasthan, Shastrakarma Vidhi
Source: Astanga Hridaya Sutrasthan, Dvividha Upakramaneeya; Snehavidhi oleation therapy; Dhumpana Medicated Smoking; Shastrakarma Vidhi
The fumigation with jatu (lac), sevya (Vetiveria zizanoides), patra (Cinnamomum tamala), guggulu (Commiphora mukul), bhallataka (Semecarpus anacardium), flower of kakubha (Terminalia arjuna), sarjarasa (Vateria indica) and shveta (Clitoria ternatea) is an excellent remedy for curing poisoning by snake and rat bite.
— Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 23: Poison Treatment (Visha Chikitsa / विषचिकित्सा)
Devadaru (Cedrus deoda), haridra, (Curcuma longa), daruharidra (Berberis aristata), sarala (Pinus longifolia), chandana (Santalum album), aguru (Aqualaria agallocha), rasna (Alpinio officinarum), gorochana (Bile of cow), ajaji (Cuminum cyminum), guggulu (Commiphora mukul), ikshurasa (Saccharum officinarum), nata churna, saindhava (rock salt), ananta along with cows bile and honey makes a universal remedy for poisonous bites in the quadrupeds.
— Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 23: Poison Treatment (Visha Chikitsa / विषचिकित्सा)
Linseed, guggulu (Commiphora mukul), latex of snuhi (Euphorbia neriifolia Linn.
— Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 25: Wound Management (Dwivraniya Chikitsa / द्विव्रणीयचिकित्सा)
Similarly, bhurjagranthi (nodes in the tree of Butea utilis), asmakasisa (copper sulphate), purgatives, guggulu and excrement of sparrow and pigeon should be used for depressing the wounds.
— Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 25: Wound Management (Dwivraniya Chikitsa / द्विव्रणीयचिकित्सा)
[151] One should inhale the powder of manahshila, vacha, trikatu, vidanga, hingu and guggulu.
— Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 26: Three Vital Organs Treatment (Trimarmiya Chikitsa / त्रिमर्मीयचिकित्सा)
Source: Charaka Samhita, Chikitsa Sthana — Therapeutic Principles, Chapter 23: Poison Treatment (Visha Chikitsa / विषचिकित्सा); Chikitsa Sthana — Therapeutic Principles, Chapter 25: Wound Management (Dwivraniya Chikitsa / द्विव्रणीयचिकित्सा); Chikitsa Sthana — Therapeutic Principles, Chapter 26: Three Vital Organs Treatment (Trimarmiya Chikitsa / त्रिमर्मीयचिकित्सा)
That which destroys aging and disease is called Rasayana (rejuvenative), like Amrita/Guduchi (Tinospora cordifolia), Rudanti (Capparis moonii), Guggulu (Commiphora mukul), and Haritaki (Terminalia chebula).
— Sharangadhara Samhita, Purva Khanda, Chapter 4: Dipana-Pachana Adikathanam (Digestive Actions etc.)
Guggulu should be equal to the powder, and honey should be equal to that amount.
— Sharangadhara Samhita, Madhyama Khanda, Chapter 4: Gutikakalpana (Tablet/Pill Preparations)
Shilajatu (mineral pitch) should be eight Karsha and Guggulu (Commiphora wightii) also eight Karsha.
— Sharangadhara Samhita, Madhyama Khanda, Chapter 4: Gutikakalpana (Tablet/Pill Preparations)
Yogaraja Guggulu [for Vata diseases and Amavata]: Nagara (dry ginger — Zingiber officinale), Pippalimula (root of long pepper), Pippali (long pepper — Piper longum), Chavya (Piper retrofractum), and Chitraka (Plumbago zeylanica) —.
— Sharangadhara Samhita, Madhyama Khanda, Chapter 4: Gutikakalpana (Tablet/Pill Preparations)
Yogaraja Guggulu is one of the most important Guggulu preparations in Ayurveda, considered the foremost remedy for Vata disorders, joint diseases, and rheumatic conditions.
— Sharangadhara Samhita, Madhyama Khanda, Chapter 4: Gutikakalpana (Tablet/Pill Preparations)
Source: Sharangadhara Samhita, Purva Khanda, Chapter 4: Dipana-Pachana Adikathanam (Digestive Actions etc.); Madhyama Khanda, Chapter 4: Gutikakalpana (Tablet/Pill Preparations)
Then, fumigate the wound area with powders of Guggulu (Commiphora mukul), Aguru (Aquilaria agallocha), Sarja-rasa (Vateria indica resin), Vacha (Acorus calamus), white mustard (Sinapis alba), mixed with salt and Neem (Azadirachta indica) leaves, and anoint the vital points with ghee (18).
— Sushruta Samhita, Sutra Sthana, Chapter 5: Agropaharaniya Adhyaya - Surgical Instruments and Procedures
Post-operative fumigation with antimicrobial herbs (Neem, Guggulu, Vacha are all proven antiseptics).
— Sushruta Samhita, Sutra Sthana, Chapter 5: Agropaharaniya Adhyaya - Surgical Instruments and Procedures
The ear should be fumigated with guggulu (Commiphora mukul), aguru (Aquilaria agallocha), and ghee.
— Sushruta Samhita, Uttara Tantra, Chapter 21: Chapter 21
Fumigation with guggulu is best for foul smell of the ear.
— Sushruta Samhita, Uttara Tantra, Chapter 21: Chapter 21
preparations of Bhallataka, Silajatu, Guggulu prescribed;
— Sushruta Samhita, Chikitsa Sthana, Chapter 11: Prameha Chikitsa
Source: Sushruta Samhita, Sutra Sthana, Chapter 5: Agropaharaniya Adhyaya - Surgical Instruments and Procedures; Uttara Tantra, Chapter 21: Chapter 21; Chikitsa Sthana, Chapter 11: Prameha Chikitsa
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